Scientific Staff

Mrs. Asavari JoshiAssistant Professor

Bharati Vidyapeeth, Pune

Date of Birth :18/04/1979

Department : Innovation Nutrition, IRSHA, BV (DU)

Phone : 020-24366920 (ext.520)

Educational Qualification : M.Sc. Microbiology

Designation : Assistant Professor

Research Experience:

Sept. 2023 till date, IRSHA, Pune, working as Assistant Professor
Jan. 2015 to Aug. 2023, Innovative Nutrition, IRSHA, Pune, worked as a Scientist
2007 – 2014, Piramal Life Sciences, Mumbai, worked as Research Scientist
2002 – 2006, IRSHA, Pune, worked as a Research Associate

Area of interest

Evaluating effects of linseed oil containing blends on various cellular parameters
Development of omega-3 fatty acid enriched products to improve Omega-6 to Omega-3 fatty acid ratios
Understanding effects of various nutrients and ayurvedic formulations on liver’

Honors/Awards

Received Award for significant contribution in “Drug Development of New Chemical Entity for anti-cancer activity” in 2011 (Piramal Life Sciences Ltd.)

Best Oral Presentation award at International Conference on Clinical Nutrition and Dietary Lifestyle for the paper ‘Understanding effects of flaxseed oil blends on liver cells’

Other Activities

Scientific member for the Institutional Ethics Committee, BVDUDCH, Pune
Reviewer, Journal of Ayurveda and Integrative Medicine

Research Programme

Developing omega-3 edible oil blends and evaluating their effects and safety in pre-clinical studies
Deciphering mechanism of action of flax lignan as an anti-metastatic agent in triple negative breast cancer cell line; MDA MB 231
Evaluation of the effect of outdated platelet concentrate in wound healing in patients, undergoing split thickness skin grafting

Publications

Research Articles

Bhalerao SS, Joshi AA, Khadke S, Sathiyanarayan A. Anti-obesity Effects of Triphala at Biochemical and Molecular Level in High-Fat Diet-induced Obese Rats. Pharmacognosy Magazine. 2024; 20: 30-42 (IF 1.5)
Khadke, S., Gupte, P., Mourya, A., Yadav, A., Mane, S., Joshi, A., ... & Bhalerao, S. (2023). Immunomodulatory effect of a proprietary polyherbal formulation on healthy participants: A single-blind, randomized, placebo-controlled, exploratory clinical study. Perspectives in Clinical Research, 14(3), 130-138.10.4103/picr.picr_100_22
Joshi AA, Hegde MV, Zanwar AA. Modulation of essential fatty acid levels in coconut oil with flaxseed oil. Grasas Aceites. 2023; 74: e503; (IF 1.4)
Asavari A Joshi, Mahabaleshwar V Hegde, and Anand A Zanwar. Flaxseed oil and palm olein blend to improve omega-6: omega-3 ratio. Journal of Food Science and Technology. 2022; 59:498-509 (IF 3.11)
Aniket V Mali, Asavari A Joshi, Mahabaleshwar V Hegde, and Shivajirao S Kadam. Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB- 231 to revert the TGF-β-induced epithelial–mesenchymal transition. Cancer Biology & Medicine. 2018; 15(2):137-156 (IF 4.5)
Aniket V Mali, Asavari A Joshi, Mahabaleshwar V Hegde, and Shivajirao S Kadam. Enterolactone suppresses proliferation, migration and metastasis of MDA-MB231 breast cancer cells through inhibition of uPA induced plasmin activation and MMPs-mediated ECM remodelling. APJCP. 2017; 18(4):905-915
Venkatasubbaiah A Venkatesha, Asavari A Joshi, Magesh Venkataraman, Vinay Sonawane, Prashant K Pandey, Julie Bose, Sarika A Choudhari, Dimple Bhatia, Ankita Srivastava, Vaibhavi Lad, Parkash Gill, Ramachandra Sangana, Tausif Ahmed, Anagha Damre, Vijaykumar Deore, Bichismita Sahu, Sanjay Kumar, Somesh Sharma, and Veena Agarwal. P7170, a novel inhibitor of mTORC1/mTORC2 and Activin Receptor-Like Kinase 1 (ALK1) inhibits the growth of Non Small Cell Lung Cancer. Mol Cancer. 2014; 13:259 (IF 4.77)
Archana Jalota-Badhwar, Dimple Bhatia, Srinivas Reddy Boreddy, Asavari Joshi, Magesh Venkatraman, Nikesh Desai, Sarika Chaudhari, Julie Bose, Lakshmi Sireesha Kolla, Vijaykumar Deore, Nilambari Yewalkar, Sanjay Kumar, Rajiv Sharma, Anagha Damre, Avinash More, Prakash Gill, Somesh Sharma, and Veena Agarwal. P7170: a potent and novel molecule with a unique profile of mTORC1/mTORC2, and Activin Receptor-Like Kinase 1 (ALK1) inhibition leading to anti-tumor and anti-angiogenic activity. Mol Cancer Ther. 2015; 14(5):1095-106 (IF 5.6)
Pallavi Godse, Pramod Kumar, Nilambari Yewalkar, Vijaykumar Deore, Manoj Lohar, Ramswaroop Mundada, Amol Padgaonkar, Sonal Manohar, Asavari Joshi, Dimple Bhatia, Nikesh Desai, Anagha Damre, Mandar Bhonde, Kalpana Joshi, Rajiv Sharma, and Sanjay Kumar. Discovery of P3971 an orally efficacious novel anticancer agent targeting HIF-1α and STAT3 pathways. Anticancer Agents Med Chem. 2013; 13(9):1460-6 (IF 2.3)
Sumantran VN, Joshi AK, Boddul S, Koppikar SJ, Warude D, Patwardhan B, Chopra A, Chandwaskar R, Wagh UV. Antiarthritic activity of a standardized, multiherbal, ayurvedic formulation containing Boswellia serrata: in vitro studies on knee cartilage from osteoarthritis patients. Phytotherapy Research. 2011;25(9):1375-80. (IF 6.0)
Venil N Sumantran, Asavari Kulkarni, Rucha Chandwaskar, Abhay Harsulkar, Bhushan Patwardhan, Arvind Chopra, and Ulhas V Wagh. Chondroprotective Potential of Fruit Extracts of Phyllanthus emblica in Osteoarthritis. Evid Based Complement Alternat Med. 2008; 5(3):329-35 (IF 2.65)
Venil N Sumantran, Rucha Chandwaskar, Asavari Kulkarni Joshi, Sanjay Boddul, Bhushan Patwardhan, Arvind Chopra, and Ulhas V Wagh. The relationship between chondroprotective and antiinflammatory effects of Withania somnifera root and glucosamine sulphate on human osteoarthritic cartilage in vitro. Phytother Res. 2008; 22(10):1342-8 (IF 6.0)
Venil N Sumantran, Asavari A Kulkarni, Abhay Harsulkar, Asmita Wele, Soumya J Koppikar, Rucha Chandwaskar, Vishakha Gaire, Madhuri Dalvi, and Ulhas V Wagh. Hyaluronidase and collagenase inhibitory activities of the herbal formulation Triphala guggulu. J Biosci. 2007; 32(4):755-61
Venil N Sumantran, Asavari Kulkarni, Sanjay Boddul, Trushna Chinchwade, Soumya J Koppikar, Abhay Harsulkar,Bhushan Patwardhan, Arvind Chopra, and Ulhas V Wagh. Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis. J Biosci. 2007; 32(2):299-307

Books

Bodhankar S, Hegde MV, Joshi AA, Zanwar AA. Jeevandayinee Jawas (2023), Goldenpage Publications, Pune, India. ISBN: 978-81-965069-4-0

Chapters in Books

Asavari A. Joshi , Mahabaleshwar V. Hegde and Sharad P. Adekar. Omega-3 Fatty Acids in Cancer: Insight into the Mechanism of Actions in Preclinical Cancer Models. In: Anand A. Zanwar, Sharad P. Adekar and Mahabaleshwar V. Hegde, ed(s). Omega-3 Fatty Acids – Keys to Nutritional Health. Switzerland: Springer International Publishing; 2016:157-172.
Zanwar, A. A., Joshi, A., & Hegde, M. V. Effects of Dietary Omega-3 Fatty Acid Consumption. In Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases. eBook ISBN: 9780128119600 Paperback ISBN: 9780128119594. Imprint: Academic Press, 2018; 385-399
Asavari A Joshi and Anand A Zanwar. Effect of olive oil on metabolic syndrome. Olives and Olive Oil in Health and Disease Prevention. Academic Press, 2021; 261-272