Educational qualification
MSc Virology, Ph.D. Biotechnology (Virology) from National Institute of Virology, Pune
Professional Experience
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Assistant Professor, IRSHA - 2017 till date
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Research Associate (2016-2017), IRSHA
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Ph.D. (2010-2016), National Institute of Virology, Pune
Research Interests
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Assay development and validation – ELISA, cell-culture based tests for virus titration, virus neutralization
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Immune response to viral infections and vaccines
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Infectious disease epidemiology – Molecular surveillance, sero-epidemiological investigations for viral diseases
Regulatory Responsibility
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Working as Technical Manager in NABL accredited laboratory at IRSHA, since 2018.
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Working as Analytical Project Manager at National Immunogenicity and Biologics Evaluation Center (NIBEC) since 2020, with responsibility for management of immunogenicity testing for viral vaccine clinical trials.
Publications
Link to access my publications https://scholar.google.com/citations?user=I1ms5lMAAAAJ&hl=en
Journal articles (last 5 years):
Book chapter:
Kulkarni R. Antibody-Dependent Enhancement of Viral Infections. Dynamics of Immune Activation in Viral Diseases. 2019 Nov 5:9–41. doi: 10.1007/978-981-15-1045-8_2. PMCID: PMC7119964.
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Arankalle VA, Kulkarni-Munje A, Kulkarni R, Palkar S, Patil R, Oswal J, Lalwani S, Mishra AC. Immunogenicity of two COVID-19 vaccines used in India: An observational cohort study in health care workers from a tertiary care hospital. Front Immunol. 2022; In press.
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Patil HP, Gosavi M, Kulkarni R, Mishra AC, Arankalle VA. Immunoglobulin G Subclass Response After Chikungunya Virus Infection. Viral Immunol. 2022 Jul;35(6):437-442. doi: 10.1089/vim.2022.0055. Epub 2022 Jul 15. PMID: 35838586.
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Malshe N, Patnaik SK, Lalwani S, Suryawanshi P, Kulkarni R, Mhaske S, Mishra AC, Arankalle V. Perinatal transmission of SARS-CoV-2 and transfer of maternal IgG/neutralizing anti-SARS-CoV-2 antibodies from mothers with asymptomatic infection during pregnancy. Infection. 2021 Jul 7:1–7. doi: 10.1007/s15010-021-01650-5. Epub ahead of print. PMID: 34232457; PMCID: PMC8262126.
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Kulkarni R, Shrivastava S, Patil HP, Kore P, Rane P, Palkar S, Lalwani S, Mishra AC, Arankalle VA. Performance assessment of SARS-CoV-2 IgM & IgG ELISAs in comparison with plaque reduction neutralization test. Indian J Med Res. 2021 May&Jun;153(5&6):658-664. doi: 10.4103/ijmr.IJMR_3806_20. PMID: 34145085.
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Kulkarni R, Patil HP, Palkar S, Lalwani S, Mishra AC, Arankalle V. Anti-SARS-CoV-2 IgG antibody response among Indian COVID-19 patients using β-propiolactone-inactivated, whole virus-based indirect ELISA. J Virol Methods. 2021 Jan;287:113996. doi: 10.1016/j.jviromet.2020.113996. Epub 2020 Oct 22.PMID: 33126149; PMCID: PMC7581401.
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Gopalkrishna V, Ganorkar N, Patil P, Hedda G, Ranshing S, Kulkarni R. Clinical, epidemiological, and molecular aspects of picornaviruses (entero, parecho) in acute gastroenteritis: A study from Pune (Maharashtra), Western India. J Med Virol. 2021 Jun;93(6):3590-3600. doi: 10.1002/jmv.26571. Epub 2020 Oct 14. PMID: 32997382.
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Kulkarni R, Shrivastava S, Patil HP, Tiraki D, Mishra AC, Arankalle VA. Correlation of serostatus and viraemia levels among Indian dengue patients at the time of first diagnosis. Trans R Soc Trop Med Hyg. 2020 Jul 1;114(7):513-520. doi: 10.1093/trstmh/traa027. PMID: 32484863.
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Kulkarni R, Modak M, Gosavi M, Wani D, Mishra AC, Arankalle VA. Comparative assessment of commercial enzyme-linked immunosorbent assay & rapid diagnostic tests used for dengue diagnosis in India. Indian J Med Res. 2020 Jan;151(1):71-78. doi: 10.4103/ijmr.IJMR_613_18. PMID: 32134017; PMCID:PMC7055168.
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Arankalle VA, Kulkarni R, Malshe N, Palkar S, Lalwani S, Mishra AC. Seroepidemiology of respiratory syncytial virus in western India with special reference to appropriate age for infant vaccination. J Med Virol. 2019 Aug;91(8):1566-1570. doi: 10.1002/jmv.25489. Epub 2019 May 6. PMID: 31012488.
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Malshe N, Palkar S, Kulkarni R, Lalwani S, Mishra AC, Arankalle V. Early disappearance of maternal anti-measles, mumps, rubella, and varicella antibodies in Indian infants. Vaccine. 2019 Mar 7;37(11):1443-1448. doi:10.1016/j.vaccine.2019.01.043. Epub 2019 Feb 11. PMID: 30765170.
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Arankalle V, Tiraki D, Kulkarni R, Palkar S, Malshe N, Lalwani S, Mishra A. Age-stratified anti-HAV positivity in Pune, India after two decades: Has voluntary vaccination impacted overall exposure to HAV? J Viral Hepat. 2019 Jun;26(6):757-760. doi: 10.1111/jvh.13074. Epub 2019 Mar 5. PMID: 30739364.
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Kulkarni R, Tiraki D, Wani D, Mishra AC, Arankalle VA. Risk of transfusion-associated dengue: screening of blood donors from Pune, western India.Transfusion. 2019 Feb;59(2):458-462. doi: 10.1111/trf.15007. Epub 2018 Nov 10.PMID: 30727040.
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Kulkarni R, Lole K, Chitambar SD. Use of rabbit antibodies raised against Norovirus GII.4 virus-like particles for diagnosis of Norovirus infection. Indian J Med Res. 2017 Dec;146(6):788-790. doi:10.4103/ijmr.IJMR_463_16. PMID: 29664039; PMCID: PMC5926352.
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Kulkarni R, Walimbe AM, Chitambar SD. Spatiotemporal evolutionary dynamics of norovirus GII.4 variants. Adv Pediatr Res 2019. 4:5. doi:10.12715/apr.2017.4.5