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Dr. Supriya BhaleraoProfessor

Bharati Vidyapeeth, Pune

Date of Birth : 09-07-1972

Department : Obesity-Diabetes

Phone : 020-24369920 (ext. 202)

Educational Qualification : MD, PhD (Ayurveda), PG Diploma in Bioethics

Email : supriya.bhalerao@bharatividyapeeth.edu, supriya.bhalerao@gmail.com

Research Experience :

  • Professor, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to be University), Pune, India (September 2023 - till date)
  • Associate Professor, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to be University), Pune, India (July 2013 - August 2023)
  • Research Officer, Sharadini Dahanukar Advanced Centre for Ayurveda Research, Training & Services (SD-ACARTS), TNMC & BYL Nair Ch. Hospital, Mumbai (July 2001-June 2013)
  • Research Fellow, Ayurveda Research Centre, GSMC & KEMH, Mumbai (Feb 1999-June 2001)

Area of Interest

  • Diabetes
  • Validation of herbal interventions through mechanistic studies
  • Lifestyle interventions

Honors/Awards

  • Member, Expert Committee for Products Approval, FSSAI, Ministry of Health & Family Welfare
  • Member of World Health Organization Global Center for Traditional Medicine Editorial Board/Task Force (WHO-GCTM-EB).
  • Member, Data Safety Monitoring Board, or monitoring of clinical trials and population-based prophylactic studies of AYUSH interventions related to COVID-19 under Ministry of Ayush

Other Activities

  • Chairperson/member of various ethics committee
  • Member of Editorial review board, Journal of Ayurveda and Integrative Medicine
  • MUHS approved faculty for Research Methodology and Biostatistics

Professional Memberships

  • Life Member of Indian Pharmacological Society
  • Life Member of International Association for the Study of Traditional Asian Medicine (IASTAM) India
  • Life Member of Mumbai Immunology Group
  • Member, Society for Ethnopharmacology- India, Pune Chapter

Publications

  • Total Published articles : 68
  • Book Chapters : 6

Research Programmes

The broad aim of my research is to generate and strengthen evidence base for Traditional Medicine therapies/practices for the prevention and management of obesity, diabetes, and other insulin-resistant conditions. Though Lifestyle modification remains cornerstone of the management of these metabolic diseases, it has limited success due to poor compliance. Conversely, conventional pharmacotherapy is associated with adverse effects of varied severity. This warrants for a search of safe and cost-effective therapies/practices.

The major hallmark of metabolic diseases is adipose tissue dysfunction leading to insulin resistance, chronic low grade inflammation and oxidative stress. My group is investigating effect of herbal formulations and therapeutic procedures from Ayurveda as well as mind-body practices from yoga on these key pathophysiological processes using advanced techniques.

Being a clinician-researcher, my core expertise lies in conducting clinical studies. However, complementary studies using in vitro and in vivo models are also undertaken by my group to understand the mechanisms of the selected interventions.

Publications

Original articles:

  • Bhapkar, V., Giramkar, S., & Bhalerao, S. (2024). Differences in Perception of Body Image among Young and Older Adult Women from Pune City, Maharashtra: A Cross-Sectional Study. Journal of Ayurveda, 18(1), 28-36.
  • Bhalerao, S. S., Joshi, A. A., Khadke, S., & Sathiyanarayan, A. (2024). Anti-obesity Effects of Triphala at Biochemical and Molecular Level in High-Fat Diet-induced Obese Rats. Pharmacognosy Magazine, 20(1), 30-42.
  • Sharma, N., Raina, P., Mulla, G., Shindikar, A., Patil, P., Bhalerao, S., & Kaul-Ghanekar, R. (2024). Phytochemical Profiling and Assessment of Habbe Musaffe Khoon Against Cervical Cancer. Pharmacognosy Magazine, 09731296231204132.
  • Shital Giramkar, Supriya Bhalerao, Manasi Deshpande. (2024). Utilization of Triphala by Ayurvedic physicians for management of obesity: a cross-sectional study. Annals of Ayurvedic Medicine. 12 (4): 320-326
  • S. Giramkar, S., Mane, S., Dolle, A., Shirodkar, J., & Bhalerao. (2024) Effect of Different Processing Methods on Composition, Biological Activities and Permeability of Barley (Hordeum vulgare L.): An Indigenous Cereal. Journal of Natural Remedies. 24 (1): 79-87
  • Bhapkar, V., & Bhalerao, S. (2024). Fighting COVID-19: A Study to Compare Viable Treatment Options across Different Medical Systems. International Journal of Ayurvedic Medicine, 15(1), 13–21. https://doi.org/10.47552/ijam.v15i1.4416
  • Shital Giramkar, Sarika Mane, Abhilasha Dolle, Jyoti Shirodkar and Supriya Bhalerao. (2024) Effect of Different Processing Methods on Composition, Biological Activities and Permeability of Barley (Hordeum vulgare L.): An Indigenous Cereal. Journal of Natural Remedies. 24 (1):79-87
  • Chitrakar, M., Bhalerao, S., Pawar, V., & Bhapkar, V. (2023). Evaluation of Memory and Cognition Enhancing Activity of Glycerrhiza glabra Linn. Formulation Along with Yoga in Teenage (13-16 years) Students. Journal of Natural Remedies, 255-262.
  • Ulhe, A., Sharma, N., Mahajan, A., Patil, R., Hegde, M., Bhalerao, S., & Mali, A. (2023). Decoding the therapeutic landscape of alpha-linolenic acid: a network pharmacology and bioinformatics investigation against cancer-related epigenetic modifiers. Journal of Biomolecular Structure and Dynamics, 1-26.
  • Gupte, P. A., Khade, K. N., Wagh, G. N., Deshmukh, C. S., Pandit, V. A., & Bhalerao, S. S. (2023). Effect of combination of Curcuma longa with Emblica officinalis in females with polycystic ovarian syndrome: An open-label, randomized active-controlled, exploratory clinical study. Journal of Diabetology, 14(3), 126-134.
  • Khadke, S., Gupte, P., Mourya, A., Yadav, A., Mane, S., Joshi, A., & Bhalerao, S. (2023). Immunomodulatory effect of a proprietary polyherbal formulation on healthy participants: A single-blind, randomized, placebo-controlled, exploratory clinical study. Perspectives in Clinical Research, 14(3), 130-138.
  • Poonam A Gupte, Kalyani N Khade, Girija N Wagh, Chaya S Deshmukh, Vijaya A Pandit, Supriya S Bhalerao. (2023). Effect of combination of Curcuma longa with Emblica officinalis in females with polycystic ovarian syndrome: An open-label, randomized active-controlled, exploratory clinical study. Journal of Diabetology. 14 (3): 126 – 134
  • Bhapkar, V., & Bhalerao, S. (2022). Relation of spice consumption with COVID-19 first wave statistics (infection, recovery and mortality) across India. International Journal of Ayurvedic Medicine, 13(3), 699–705. https://doi.org/10.47552/ijam.v13i3.3024
  • Bhalerao S., Kharche J., Harke S. (2022). Effect of yoga intervention on skeletal muscle linked glucose homeostasis in pre-diabetic individuals: Study protocol for a randomized controlled trial. Advances in Integrative Medicine, 9 (4), pp. 230 – 234. 10.1016/j.aimed.2022.11.002
  • Gupte PA, Giramkar SA, Bhalerao SS. (2022). Influence of socio-economic status on lifestyle preferences contributing to childhood obesity: A cross-sectional study. Med J DY Patil Vidyapeeth. 2022: 15(4): 565-571
  • Shital Giramkar, Anand Zanwar, Supriya Bhalerao. (2022) Comparative Evaluation of Triphala Extract Prepared Using Two Methods. Indian Journal of Pharmaceutical Sciences. 82 (2):513.
  • Gupte P., Mahajan M., Revadkar Kole M., Mandlecha A., Tatke P., Naharwar V., Bhalerao S. (2022). Efficacy and acceptability of pomegranate effervescent granules in patients suffering from acid peptic disorders. Indian Journal of Pharmacology, 54 (1), pp. 7 – 12. 10.4103/ijp.ijp_914_20
  • Bhapkar V., Sawant T., Bhalerao S. (2022). A critical analysis of CTRI registered AYUSH studies for COVID- 19. Journal of Ayurveda and Integrative Medicine, 13(1), 100370. 10.1016/j.jaim.2020.10.012
  • Sharada Hendre, Poonam Gupte, Supriya Bhalerao, Madhavi Mahajan, Ajit S Kolatkar. (2022). Usefulness of Gastropanel for Validation of Efficacy of Drugs from Traditional Systems of Medicine in Functional Dyspepsia. Asian Pacific Journal of Health Sciences. 9, 4(S).
  • Mane S., Dixit K.K., Lathwal N., Dhotre D., Kadus P., Shouche Y.S., Bhalerao S. (2021). Rectal administration of buttermilk processed with medicinal plants alters gut microbiome in obese individuals. Journal of Diabetes and Metabolic Disorders, 20 (2): 1415 - 1427.10.1007/s40200-021-00879-z
  • Gupte PA, Giramkar SA, Harke SM, Kulkarni SK, Deshmukh AP, Hingorani LL, Mahajan MP, Bhalerao SS. (2019). Evaluation of the efficacy and safety of Capsule Longvida® Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study. Journal of Inflammation Research. 12:145
  • Salunke M, Banjare J, Bhalerao S. (2019). Effect of selected herbal formulations on anthropometry and body composition in overweight and obese individuals: A randomized, double blind, placebo-controlled study. Journal of Herbal Medicine.17-18: 100298.
  • Gupte P, Harke S, Deo V, Shrikhande BB, Mahajan M, Bhalerao S. (2019). A clinical study to evaluate the efficacy of Herbal Formulation for Obesity (HFO-02) in overweight individuals. J Ayurveda Integr Med. 11(2):159-162.
  • Mahajan Madhavi, Kulkarni Sneha, Deo Veena, Shrikhande Bharatbhushan and Bhalerao Supriya. (2017). Capsule Ibomic a Polyherbal Formulation for the Treatment of Irritable Bowel Syndrome Type - D: A Case Series. Int J Ayu Pharm Chem 7(1):103-110
  • Banjare Jyotibala, Raina Prerna, Mansara Prakash, Kaul-Ghanekar Ruchika & Bhalerao Supriya. (2017). Triphala, Regulates Adipogenesis through Modulation of Expression of Adipogenic Genes in 3T3-L1 Cell Line. Pharmacognosy Magazine. 13. S834-S839. 10.4103/pm.pm_153_17
  • Bhalerao Supriya, Munshi Renuka & Joshi Samidha. (2017). Evaluation of the anti-inflammatory effect of Yograj Guggul: an in vitro study. International Journal of Phytomedicine. 9. 498. 10.5138/09750185.2122
  • Salunke Megha, Deshpande Manasi & Bhalerao Supriya. (2017). Experiential documentation of Trimad for its anti-obesity potential: A survey of Ayurvedic physicians from Pune city. Journal of Ayurveda and Integrative Medicine. 8. 10.1016/j.jaim.2017.03.004.
  • Salunke Megha, Giramkar Shital, Bhalerao Supriya. (2017). In vitro free radical scavenging potential of trimad (a polyherbal formulation). International Journal of Research in Ayurveda & Pharmacy. 8. 127-131. 10.7897/2277-4343.083183.
  • Banjare Jyotibala, Salunke Megha, Indapurkar Kavita, Ghate Umesh & Bhalerao Supriya. (2017). Estimation of serum malondialdehyde as a marker of lipid peroxidation in medical students undergoing examination-induced psychological stress. Journal of the Scientific Society. 44. 137. 10.4103/jss.JSS_13_17.
  • Dawane, J. S., Pandit, V., Khade, K. S., Suryawanshi, S. P., Wele, A., Pawar, M., & Bhalerao, S. (2017). Study the efficacy of herbal formulation Nisamalaki in animal model of polycystic ovarian disease syndrome. Ancient Science of Life, 37(2), 86-93.Review Papers
  • Bhalerao Supriya, Mohite Swati, Kulkarni Sneha, Deo Veena, Shrikhande BK. (2016). Effect of Lucronil® Tablets in the Patients with Leucorrhea: An Open Clinical Trial. International Journal of Science and Research. 5 (10);1338:1342.
  • Wele Asmita, Pendse Nikhil, Takle Shrikant, Burase Raghunath, Patil, Sanjay, Bhalerao Supriya & Harsulkar Abhay. (2016). "Ayurvedic hydro-alcoholic anti-asthmatic medicine Vasarishta built upon MritasanjeevaniSura: Development and evaluation". AYU (An international quarterly journal of research in Ayurveda). 36. 10.4103/0974-8520.182746.
  • Munshi Renuka, Bhalerao Supriya, Nesari Tanuja. (2016). Evaluation of the efficacy of Brahmi ghrita in scopolamine induced amnesia in rats using Cook's pole apparatus. International Journal of Basic and Clinical Pharmacology. 829-833. 10.18203/2319-2003.ijbcp20161529.
  • Panchal FH, Ray S, Munshi RP, Bhalerao SS, Nayak CS. (2015) Alterations in Lipid metabolism and Antioxidant Status in Lichen Planus. Indian Journal of Dermatology; 60(5): 439–444
  • Salunke M, Banjare J, Khadke S, Harke S, Kuvalekar A, Diwan A, Pankaj M, Shukla S, Ranjekar P, Bhalerao S. (2015). Estimation of serum Copeptin (A novel marker of metabolic syndrome) in patients with type 2 diabetes mellitus. J Obes Metab Res. 2:191-4
  • Thatte U, Chiplunkar S, Bhalerao S, Kulkarni A, Ghungralkar R, Panchal F, Vetale S, Teli P, Kumbhar D, Munshi R. (2015) Immunological & metabolic responses to a therapeutic course of Basti in obesity. Indian J Med Res.142:53-62
  • Khadke S, Harke S, Ghadge A, Kulkarni O, Bhalerao S, Diwan A, Pankaj M, Kuvalekar A. (2015) Association of Fasting Plasma Glucose and Serum Lipids in Type 2 Diabetics. Indian J Pharm Sci. 77(5):630-4.
  • Munshi RP, Bhalerao SS, Kalekar SA, Patil TA. (2014) Exploration of the Angiogenic Potential of Honey. British Journal of Pharmaceutical Research. 4(4): 477-489
  • Basavarajeshwari, R.R.Hiremath, Supriya.Bhalerao. (2014). Hypoglycaemic effect of Madhumeha kashaya Ghana in Streptozotocin induced Diabetic Wistar rats. Indian Journal of Applied Research. 4(12): 438-439
  • Kalekar SA, Munshi RP, Bhalerao SS, Thatte UM. (2013) Insulin sensitizing effect of 3 Indian medicinal plants: An in vitro study. Indian J Pharmacol.45:30-3
  • Bhalerao Supriya, Munshi Renuka, Nesari Tanuja, Shah H. (2013) Evaluation of Brahmighritam in children suffering from Attention Deficit Hyperactivity Disorder. Ancient Sci Life;33:123-30
  • Bhalerao S, Deshpande T, Thatte U. (2012) Prakriti (Ayurvedic concept of constitution) and variations in platelet aggregation BMC Complementary and Alternative Medicine, 12:248 doi:10.1186/1472-6882-12-248
  • Sharma U, Bhalerao SS, et al (2012). Polysaccharide enriched immunomodulatory fractions from Tinospora cordifolia (Willd) miers ax hook. f. & Thoms. Indian J Exp Biol. 50 (9):612-7
  • Dalvi AA, Bhalerao SS, Munshi RP. (2012) Effect of aqueous extract of bark of Alstoniascholaris Linn. on respiratory burst in Polymorphonuclear neutrophils (PMNs). IJRAP 3(5): 720-723
  • Sharma U, Bhalerao SS, et al (2012). Immunomodulatory active steroidal saponins from Asparagus racemosus. Medicinal Chemistry Research., doi: 10.1007/s00044-012-0048-4
  • Sharma, U, Bhalerao SS, et al (2012). Immunomodulatory active compounds from Tinospora cordifolia. J. Ethnopharmacol. doi:10.1016/j.jep.2012.03.027
  • Kalekar S, Karve A, Munshi R, Bhalerao S. (2012) Evaluation of the Adipogenic potential and glucose uptake stimulatory activity of Phyllanthus emblica and Tinospora cordifolia: an in vitro study. International Journal of Pharma and Bio Sciences. 3 (1): 230-236
  • Munshi R, Bhalerao S, Rathi P, Kuber VV, Nipanikar SU, Kadbhane KP. (2011) An open-label, prospective clinical study to evaluate the efficacy and safety of TLPL/AY/01/2008 in the management of functional constipation. J Ayurveda Integr Med. 2(3):144-52

Other articles:

  • Vijayanna, S. T., Mane, S., Bhalerao, S., & Jaideep, S. S. (2024). Ayurvedic Therapies to Target the Microbiome: Evidence and Possibilities. Alternative Therapies in Health and Medicine, AT6960-AT6960.
  • Bhapkar V., Bhalerao S. (2022). Dissemination of COVID-19 research: Time to walk the talk. Journal of Ayurveda and Integrative Medicine, 13 (1). 100459. 10.1016/j.jaim.2021.05.013
  • Rahul Palshetkar, Supriya Bhalerao, Akshaykumar Challani, Amit Khandare and Santosh Tale. Evaluation of Ayurvedic protocol In the management of Coronary Artery Disease. 2022. 9 (1), 450-456.
  • Gupte, P., & Bhalerao, S. (2021). Book review of’Integrative Ayurveda-Proceedings of Workshop and National Seminar: Tadvidya Sambhasha Ayurveda XII, 2017’edited by Dr. Rama Ashok Vaidya and Ms. Roda Dalal.
  • Bhalerao Supriya, Ranade Anagha, Vaidya Ashok. (2017). Letter to editor. Journal of Ayurveda and Integrative Medicine. 8. 10.1016/j.jaim.2017.01.002.
  • Bhalerao S, Ranade A, Vaidya AD. Bloom's taxonomy reiterates Pramana. J Ayurveda Integr Med. 2017 Jan-Mar;8(1):56-57.
  • Bhalerao Supriya, Patwardhan Kishor. (2016). Prakriti-based research: Good reporting practices. Journal of Ayurveda and Integrative Medicine. 7. 10.1016/j.jaim.2015.08.002.
  • Salunke M, Bhalerao. (2016). Anti-Obesity Effect of Trimad, a Polyherbal Formulation: A Review Int. J. Pharm. Sci. Rev. Res.
  • Bhalerao Supriya & Prasad BS (2016). Attitude of interns towards research as a career option. Journal of Ayurveda and Integrative Medicine. 7. 10.1016/j.jaim.2015.06.001.
  • Banjare Jyotibala, Bhalerao Supriya. (2016). A survey of marketed ayurvedic/herbal anti-obesity products. Int J Pharm Pharm Sci. 8(8):384-386
  • Banjare J, Bhalerao S. (2016). Obesity associated non-communicable disease burden. International Journal of Health & Allied Sciences; 5(2): 81-87
  • Telang-Chaudhari, S., Baxi, G. D., & Bhalerao, S. (2014). Competency based education in Ayurveda: Need of the hour?. Ancient Science of Life, 34(2), 119-120.
  • Belhekar MN, Bhalerao SS, Munshi RP. (2014) Ethics reporting practices in clinical research publications: A review of four Indian journals. Perspect Clin Res. 5:129-33
  • Bhalerao S, Munshi R, Tilve P and Kumbhar D. (2010) A survey of the labeling information provided for ayurvedic drugs marketed in India. Int J Ayurveda Res.; 1(4): 220–222.
  • Parab S, Bhalerao. (2010). Choosing statistical test. Int J Ayurveda Res. 1:187-91
  • Parab S, Bhalerao. (2010). Study designs. Int J Ayurveda Res. 1:128-31
  • Kadam P, Bhalerao S.(2010). Sample size calculation. Int J Ayurveda Res. 1:55-7
  • Bhalerao S, Godse C. (2010). Malaria: Ayurvedic Approach for Management and Potential of Medicinal Plants. The Journal of General Medicine, 22(2): 42-6
  • Thatte U, Bhalerao S. (2008). Pharmacovigilance of ayurvedic medicines in India. Indian J Pharmacol. 40:10-2
  • Thatte UM and Bhalerao SS. (1999). Ayurveda and Liver Diseases. The Journal of General Practice. 26(6): 46-50.

Review Papers 

  • Salunke M, BhaleraoS. Anti-Obesity Effect of Trimad, a Polyherbal Formulation: A Review Int. J. Pharm. Sci. Rev. Res. 2016
  • Banjare J, Bhalerao S. Obesity associated non-communicable disease burden. International Journal of Health & Allied Sciences 2016; 5(2): 81-87
  • Parab S, Bhalerao S. Choosing statistical test. Int J Ayurveda Res 2010;1:187-91
  • Parab S, Bhalerao S. Study designs. Int J Ayurveda Res 2010; 1:128-31
  • Kadam P, Bhalerao S. Sample size calculation. Int J Ayurveda Res 2010; 1:55-7
  • Bhalerao S, Godse C. Malaria: Ayurvedic Approach for Management and Potential of Medicinal Plants. The Journal of General Medicine, 2010; 22(2): 42-6
  • Thatte U, Bhalerao S. Pharmacovigilance of ayurvedic medicines in India. Indian J Pharmacol 2008; 40:10-2
  • Thatte UM and Bhalerao SS. Ayurveda and Liver Diseases. The Journal of General Practice, 1999; 26(6): 46-50.

Chapter in Book

  • Chitrakar M, Bhalerao S; Basics concepts of nutrition in Ayurveda, CRC Press, 2024, Therapeutic Nutrition in Ayurveda, pp:2-20
  • Patwardhan, K., Bhalerao, S., Chakrabarti, S.S. Plagiarism: Emerging Challenges and Potential Solutions. In: Joshi, P.B., Churi, P.P., Pandey, M. (eds) 2024. Scientific Publishing Ecosystem. Springer, Singapore. PP 59-77.
  • Mathangi DC, Bhalerao S; Potential role of traditional medicine in stem cell research, Elsevier, 2023, Stem Cells and Signaling Pathways, pp: 451-460
  • Wagh K., Bhalerao S. Traditional foods, Ayurveda, and diet. 2020. Nutritional and Health Aspects of Food in South Asian Countries, pg. 99 – 111.
  • Dahanukar SA, Thatte UM, Bhalerao SS; Current status in fertility regulation: Indigenous & modern approaches, CDRI, 2001, Herbal drugs for fertility regulation, pg: 67-89
  • Thatte UM, Bhalerao SS; Regulations in Clinical Research on Traditional Medicine, ICMR, 2013, Regulatory Requirement in Drug development and Clinical Research, pg: 299-314

 

 

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