Department of General Medicine

Research

The Department of General Medicine is committed to contributing to medical science and improving patient health care. Our researchers conduct innovative research with a focus on developing preventive and therapeutic strategies and providing advanced treatment options.

Research Areas

The Department has their research areas on Vaccine Trails and COVID Research. They are keener towards the safety and measures to be taken during the COVID times.

Research Projects

The Department of General Medicine offers exceptional research opportunities for students. The various research activities of the department includes Completed Major and Minor Research Projects.

Major Project

Studies on Glycation Induced modifications in Diabetes Mellitus in Diabetes Study of RAGE in Type II Diabetes in collaboration with Rajiv Gandhi Institute of Information Technology and Biotechnology & Research Society for Study of Diabetes in India

Minor Projects

Role of Vitamin D in Type 2 Diabetes Mellitus
Inflammatory Markers in Type 2 Diabetes Mellitus
Iron Status in Type 2 Diabetes Mellitus and its co-relation with Insulin Resistance

Sr.No	Title of project	Date of sanctioning of project	Date of starting of project	Probable date of completion of project	Duration of Project in months	Name of Principal investigator	Name/s of co-investigators
1	Feasibility of the Home Isolation Programme for adults and children with COVID 19 Patients	01/08/2020	01/07/2020	30th Sept 2020	3 Months	Dr. Purwa Doke	Dr. Jitendra Oswal, Dr. Disha Padalkar, Dr. Mohit Jain
2	Anti- coronavirus therapies (ACT) to prevent progression of COVID 19 trial		01-Jul-20	31st July 2020	1 month	Dr. Purwa Doke	Dr. Shivakumar Iyer, Dr. Jignesh Shah, Dr. Sujata rege
3	Anti –Coronavirus Therapies (ACT) to prevent progression of COVID 19: Randomized trails		30/6/2020	30/12/2020	6 Months	Dr. Purwa Doke
4	Clinical Profile of COVID -19 infected patients admitted in a Tertiary Care Hospital in Western INDIA	09/07/2020	01-Jul-20	1st July 2021	12 months	Dr. Supriya Barsode	Dr. (Col) V.P.Singh, Dr. Arundhati Diwan, Dr. Nitin Gadkari, Dr. Rishi Patel
5	Risk Factor association and development of severity prediction score in COVID -19 patients	27/07/2020	31/07/2020	31-Jul-20	3 months	Dr. Sujata Rege	Dr. Gargee Pore, Dr. Amit Nisal, Dr. Meghana Padwal, Dr. A.A.Momin
6	Protocol Title: A phase 2 evaluation of the efficacy of homeopathic remedy Zincum Muriaticum as an adjuvant therapy to standard of care in adult subjects with moderate to severe COVID-19: Randomised, double blind, parallel group, placebo controlled, multicenter trial (ZIMCOV)	21/10/2020			12 months	Dr. Prachee Makashir
7	A Prospective, Open Label, dose escalation phase I clinical study to evaluate the safety, tolerability and immunogenicity of Reliance Life Sciences SARS-coV -2 Recombiant protein subunit vaccine in healthy volunteers.	29/12/2021	17/1/2022	16/6/2022	6 mths	Dr.Prachee Makashir	Dr.Purwa Doke, Dr.Swati Chouhan, Dr.Bhabatosh Saha

Publications

In the last five years, the faculty members of the Department of General Medicine have published 125 works in the form of case reports and original articles with the active participation of the postgraduate students.

Sr.No	Title	Author	Journal	Year
1	TNFA and IL10 Polymorphisms and IL-6 and IL-10 Levels Influence Disease Severity in Influenza A(H1N1)pdm09 Virus Infected Patients	Kalichamy Alagarasu, Himanshu Kaushal, Pooja Shinde, Mahadeo Kakade, Urmila Chaudhary, Vikram Padbidri , Shashikala A. Sangle, Sonali Salvi, Ashish R. Bavdekar, Pradeep D’costa and Manohar Lal Choudhary,	MDPI	Dec 2021
2	The impact of COVID-19 on the postgraduate exit examination in a clinical subject	Arundhati Diwan, V. P. Singh, Sampada Karne, Supriya Barsode, Varad Nadkarni	International Journal of Advances in Medicine	Sep 2021
3	Two-Gene Signature for Tuberculosis Diagnosis in Persons With Advanced HIV	Vandana Kulkarni, Artur T. L. Queiroz, Shashi Sangle, Anju Kagal, Sonali Salvi, Amita Gupta, Jerrold Ellner, Dileep Kadam, Valeria C. Rolla, Bruno B. Andrade, Padmini Salgame and Vidya Mave	Pubmed.ncbi	Feb 2021
4	Association of Body Mass Index with immune recovery ,Virological failure & casrdivascular disease risk among people living with HIV , HIV Medicine	W M Han;, A Jiamsakul Jantarapakde;, E Yunihastuti;, R Ditangco, R Chaiwarith, L P Sun;, S Khusuwan, T P Merati9, C D Do;, I Azwa, M-P Lee, K Van Nguyen, Y-J Chan; S Kiertiburanakul, O T Ng; J Tanuma;, S Pujari;, F Zhang;, Y M Gani;, S Sangle; J Ross;, N Kumarasamy	Pubmed.ncbi	2021
5	Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19- associated cytokine release syndrome (COVINTOC): an openlabel, multicentre, randomised, controlled, phase 3 trial	Arvinder S Soin, Kuldeep Kumar, Narendra S Choudhary, Pooja Sharma, Yatin Mehta, Sushila Kataria, Deepak Govil, Vikas Deswal, Dhruva Chaudhry, Pawan Kumar Singh, Ashish Gupta, Vikas Agarwal, Suresh Kumar, Shashikala A Sangle, Rajesh Chawla, Suneetha Narreddy, Rahul Pandit, Vipul Mishra, Manoj Goel, Athimalaipet V Ramanan.	The Lancet Respiratory Medicine	May 2021
6	Evaluation of COVID-19 patients requiring oxygen therapy in a tertiary care teaching hospital	Priti Dave, Gargee M. Pore, V. P. Singh, Supriya S. Barsode	International Journal of Advances in Medicine	Dec 2021
7	Impact of Adherence, Patient Perception, and Knowledge to Statin Therapy – A CrossSectional Study	Siddhi Umarje, Neha M. James, Priti Dave1, Asawari Raut, Neha Pandey	Indian Journal of Endocrinology and Metabolism	May 2021
8	Association of MTHFR C677T (rs1801133) and A1298C (rs1801131) Polymorphisms with Serum Homocysteine, Folate and Vitamin B12 in Patients with Young Coronary Artery Disease	Rajni R. Shivkar, Gayatri C. Gawade Meghana K. Padwal, Arundhati G. Diwan, Sumiran A. Mahajan, Charushila Y. Kadam	Ind J Clin Biochem	May 2021
9	Clinical Profile of Covid-19 Infected Patients Admitted in a Tertiary Care Hospital in Western India,	Dr. Virendra Prasad Singh, Dr. Arundhati Diwan, Dr. Supriya Barsode, Dr. Rishi Patel, Dr. Nitin Gadkari	The Indian Practitioner	Oct 2021
10	Knowledge, Attitudes and Apprehension Regarding COVID-19 Vaccination in Healthcare Workers	Lalwani, Kajol, Regi, Jennie. K., Doke, Purwa, Pawar, Sunita	Pharmacy Practice and Research	2021
11	Clinical and Radiological Outcomes of Recovered COVID-19 Patients- An Observational Study during the Early Phase of the Pandemic,	Disha Atul Padalkar, Medha Bargaje, Purwa Prakash Doke, Sarosh Gilani, Varad Nadkarni, Sanbanki Pala	Journal of Clinical and Diagnostic Research	July 2021
12	Pheochromocytoma related intracerebral hemorrhage, hypertrophic obstructive cardiomyopathy and diabetes mellitus	Aundhati Diwan, Chandrakant Chavan, Varsha Jagtap, Priti Dave, Sampada Karne, Sumiran Mahajan, Nihal Shah	International Journal of Advances in Medicine	April 2021
13	Correlation of homocysteine and lipid profile Parameters with ischemic heart disease	Shilpa Shaunak Sule, N C Edul, R S Wadia	MedPulse International Journal of Medicine	Jan 2020
14	Evaluation of prescribing pattern and rationality of fixed dose combinations in patients of general medicine department	Nupuri Joshi1, Anvita Falke, Sajin Saji, Arundhati Diwan, Asawari Raut	International Journal of Basic & Clinical Pharmacology	Jan 2020
15	Klebsiella pneumoniae Causing Liver Abscess, Endophthalmitis, and Cavitary Pneumonia	Purwa Doke, Rajeev Soman, Bharat Purandare, Arundhati Diwan, Sumeran Mahajan, MBBS, and Shweta Panchakshari,	Infectious Diseases in Clinical Practice	July 2020
16	The burden of anxiety among people living with HIV during the COVID-19 pandemic in Pune, India	Ivan Marbaniang*, Shashikala Sangle, Smita Nimkar, Kanta Zarekar, Sonali Salvi, Amol Chavan, Amita Gupta1, 4, Nishi Suryavanshi and Vidya Mave	BMC Public Health	2020
17	Quantitative assessment of olfactory dysfunction accurately detects asymptomatic COVID-19 carriers	Anindya S. Bhattacharjeea, Samir V. Joshib, Shilpa Naikb, Shashikala Sangleb, Nixon M. Abrahama	E Clinical Medicine	Nov 2020
18	Convalescent plasma in the management of moderate COVID-19 in India: An open-label parallel- arm phase II multicentre randomized controlled trial (PLACID Trial) .,	Anup Agarwal, Aparna Mukherjee, Gunjan Kumar, Pranab Chatterjee, Tarun Bhatnagar, PankajShashikala A Sangle	BMJ Public Health Emergency Collection	Oct 2020
19	Knowledge, Attitudes, and Practices Toward Coronavirus Disease 2019 Among People in a Tertiary Care Hospital in India	Purwa Doke, MD Sujata Rege, DNB and Sonali Palkar	Infectious Diseases in Clinical Practice	Sept 2020
20	Splenomegaly – A Diagnostic Diklemma	Dr. Aarohi Doshi, Dr. Rishi Patel, Dr. Purwa Doke	The Indian Practitioner	Oct 2020
21	Analysis of patients of hemophagocytic lymphohistiocytosis Secondary to Infections	Arundhati G. Diwan, Supriya S. Barsode1, Amit R. Nisal, Ruturaj S. Deshpande, Mayur D. Patil, Neeraj S. Shettar, Vishal C. Lali1, Gargee M. Pore, Bhabatosh K. Saha	International Journal of Advances in Medicine	Oct 2020
22	Feasibility of the home isolation programme for adults and children with COVID - 19	Purwa Doke, Jitendra Oswal, Disha Padalkar, Mohit Jain	International Journal of Advances in Medicine	Nov 2020
23	Invasive fungal infection : A visible Menace	Priti Dave, Kevin Bora, Sukriti Joshi, Yashowardhan Taparia, Mayur Patil	Global Journal of Medicine & Public health	2020
24	Spurious Hyperkalemia can to be misdiagnosed and unnecessary treated	Dr. Priti Dave, Dr. Deepak Bhosle, Dr. Anuj Darak, Dr. Kathan Doshi	International Journal of Medicine Research	January 2019
25	Study Of Catheter Associated Urinary Tract Infection In A Tertiary Hospital	Priti Dave, Sumit Jagtap, Pushkar Patil, Subrat Jain	International Journal Of Scientific Research	Feb 2019
26	Study of role of pulse oxymetry during nonsedated upper gastrointestinal endoscopic procedure	Sukanya Dasgupta, Supriya Barsode	International Journal of Advances in Medicine	Aug 2019
27	Prevalence of pre diabetes in adults below 40 years with special reference to modifiable risk factors	Dr. Gadkari Nitin, Dr. Rishi Patel, Dr. Varun Chavan, Dr. Ruturaj Deshpande, Dr. Shreehari Dinesh	Journal of Medical Science and Clinical Research	April 2019
28	Study of Pleural Effusion in Chronic Kidney Disease	Dr. Gadkari Nitin, Dr. Rishi Patel, Dr. Tushar Shet, Dr. Ameya Patil, Dr. Sumiran Mahajan	Journal of Medical Science and Clinical Research	May 2019
29	Clinical profile and outcomes in patients with acute kidney Injury with and without underlying co-morbidities.	Dr. Shilpa s. Sule, Dr. Khalid i. Khatib, Dr. dileep b.Kadam, Dr. Vrushali r.Wagh	Indian Journal Of Applied Research	July 2019
30	Clinical profile of patients of acute pulmonary thromboembolism	Dr. Arundhati Diwan, Supriya Barsode, Chandrakant Chavan, Rohit Jakhotia, Krishnapriya Vadlapatla	International Journal of Advances in Medicine	June 2019
31	Predicting The Severity Of Dengue Based On A Few Clinical And Laboratory Indicators: A Retrospective Analysis	Dr. Purwa Doke, Dr. Bharat Purandare	Indian Journal Of Applied Research	Sept 2019
32	Clinicaland Biochemical Profile Of Type 2 Diabetes Patients In Ruralarea	Dr.Sujata Khatal	International Journal Of Scientific Research	Oct 2019
33	Correlation Of Incidence And Severity Of Retinopathy With Systemic Risk Factors In Type 2 Diabetes	Dr.Sujata Khatal	Indian Journal Of Applied Research	Oct 2019
34	Comperative study of different glycating agents on human plasma and vascular cells	Rashmi S Tupe1, Nilima Banger1, Arundhati Diwan2, Dhanashri Changale1, Shivani Choudhary1, Shubhangi Chaware	Molecular Biology Reports	Nov 2019
35	Study of correlation between serum vit-B12 and Homocysteine levels with ischemic heart Disease	Shilpa Shaunak Sule, N C Edul, R S Wadia	MedPulse International Journal of Medicine	Dec 2019
36	ECG Changes In Dengue Fever	Dr. Rishi Patel, Dr. Pushkar Shah	INDIAN JOURNAL OF APPLIED RESEARCH	January 2018
37	Correlation of Serum Adiponectin and Leptin levels in Obesity and Type 2 Diabetes Mellitus	Arundhati G. Diwan, Aniket A. Kuvalekar, Siddharth Dharamsi, Aditya M. Vora, Vivek A. Nikam, Abhijit A. Ghadge	Indian Journal of Endocrinology and Metabolism	March 2018
38	Levels of serum magnesium in patients with Alcoholic Liver Disease	Dr. Supriya Barsode, Arundhati Diwan, Uday Gokhale, Bhushan Rathi, Sahil Nagrani, Aviral Shah, Aditya Borawake, Ruturaj Deshpande	The Indian Practitioner	April 2018
39	Polypharmacy Induced Hyponatremia: An Additive Effect	Dr. Arundhati Diwan, Dr. Siddhi Umarje, Dr. Sunil Jawale, Dr. Asawari Raut, Dr. Aviral Shah	The Indian Practitioner	April 2018
40	A study of patients with liver cirrhosis and portal Hypertension with special reference to hematological Profile	Dr. Prachee Makashir, Dr. Siddharth Wable	Indian Journal Of Applied Research	June 2018
41	A study of critically ill obstetric patients admitted in Intensive care unit and their outcome at a tertiary care Centre	Dr. Prachee Makashir, Dr. Pratik Sethiya	Indian Journal Of Applied Research	June 2018
42	Comparison of Drug Related Problems Associated with Use of Narrow Therapeutic Index Drugs and Other Drugs in Hospitalized Patients	Kapil Iyer, Neha Dilipkumar, Sharmin Vasaya, Sunita Pawar, Arundhati Diwan	Journal of Young Pharmacists,	Oct 2018
43	Near –Peer Teaching Program for first year Residents in Medicine	Kavita Krishna. Vivek Saoji, Arundhati Diwan, Iyyer Shiva, Priti Dave, Elizabeth Sada,Prashant Zhedge	South –East Asion Journal of Medical Education	2017
44	Vitamin B12 deficiency in Chronic Kidney Disease	Dr. Rohan Patil, Dr. Deepak Bhosle, Dr .Rizwan Malik	International Organozation of Scientific Research	2017
45	Assessment of Psychological Symptoms in patients attending A Rheumatology Clinic	Dr. Gayatri Bhatia, Dr. Jyoti Shetty, Dr. Kavita Krishna, Dr. Sandesh Ghiya	International Journal of Science and Research	2017
46	Toxicological pattern of poisoning in Urban Hospitals of Western India	Dr.Dave Priti	Journal of Young Pharmacists	2017
47	Study of Clinical Profile of Guillain Barre Syndrome	Dr. Priti dave, Dr. A.G.Diwan, Dr. Baldeep Singh, Dr. Saurabh Thavare, Dr. Kunal Bonde, Dr. Bhargav Desai	Journal of Medical Science and Clinical Research	2017
48	Adipocytokines and Anthropometric measures in type 2 diabetics	Dr. Shubhangi Karke, Dr. Suresh Khadke, Dr. Abhijit Ghadge, Dr. Ashwini manglekar, Dr. Shshank Shah, Dr. Arundhati Diwan, Dr. Aniket kuvalekar	Diabetes & Metabolic Syndrome : Clinical Reseach & Reviews	2017
49	Gender dependent effects of fasting blood glucose levels and disease duration on biochemical markers in type 2 diabetics : A pilot study	Dr. Abhijit Ghadge, Dr. Arundhati Diwan, Dr. Abhay Harsulkar, Dr. Aniket kuvalekar	Diabetes & Metabolic Syndrome : Clinical Reseach & Reviews	2017
50	Study of Cognitive Impairment in type 2 Diabetis mellitus	Dr. Supriya Barsode, Dr. Lotke, Dr. Diwan	Journal of Medical Science and clinical Research	2016
51	A diverse spectrum of cardiomyopathies including atypical variants	Dr.Sachin Adukia, Dr.A.G.Diwan,	Indian Journal of applied Research	2016
52	A study of Hepatic Involvement in HIV Positive patients	Dr. K.Krishna, Dr. Gadkari, Dr. Vivek Doshi, Dr. Arundhati Diwan	Journal of Medical Science and Clinical Research	2016
53	Evaluation of Osteoporosis in Elderly with Novel Diagnostic Tools	Dr. Madhu Bansode, Dr. Pankaj Bansode, Dr. Vaibhav Lotake, Dr. Manasi Korde	Journal of Medical Science and clinical Research	2016
54	Serum Vitamin D levels in Type 2 Diabetes Mellitus –A Missing Link	Dr. Madhu Pankaj, Dr. Pankaj Bansode, Dr. A G Diwan, Dr. Chaitanya Lodha, Dr. Babhani Sahoo	Journal of Medical Science and clinical Research	2016
55	Study of Anaemia in Elderly	Dr. Priti Dave, Dr. Arundhati Diwan, Dr. Rohit Gosavi, Dr. Prajakta Patil, Dr. MD Mustaque	Indian Journal of Applied Research	2016
56	An overview of Rational prescribing pattern in Hypertensive patients in Tertiary care Hospital	Dr.Arundhati Diwan	International journal of pharmacy and Pharmaceutical Sciences	2016