Cancer Biology

Research Publication

  • Patil P., Chaudhary A., Bhandare V., Patil V., Beerwala F., Karoshi V., Sonawane K., Mali A., and Kaul-Ghanekar R., 2024; Sesamin regulates Breast Cancer through Reprogramming of Lipid Metabolism; Journal of Biomolecular Structure and Dynamics. Accepted.
  • Chaudhary A., Sharma N., Ulhe A., Mahajan A., Patil P., Bhandare V., Patil R., and Mali A, 2024; Deciphering multifaceted molecular mechanisms of Matairesinol in inhibiting Triple-Negative Breast Cancer through comprehensive systems biology investigations; Journal of Biomolecular Structure and Dynamics. Accepted.
  • Mahajan, Akanksha, Nidhi Sharma, Amrita Ulhe, Rajesh Patil, Mahabaleshwar Hegde, and Aniket Mali. "From dietary lignans to cancer therapy: Integrative systems analysis of enterolactone's molecular targets and signaling pathways in combatting cancer stem cells in triple-negative breast cancer." Food Bioscience (2024): 103732.
  • Ulhe, Amrita, Nidhi Sharma, Akanksha Mahajan, Rajesh Patil, Mahabaleshwar Hegde, Supriya Bhalerao, and Aniket Mali. "Decoding the therapeutic landscape of alpha-linolenic acid: a network pharmacology and bioinformatics investigation against cancer-related epigenetic modifiers." Journal of Biomolecular Structure and Dynamics (2023): 1-26.
  • Cervicovaginal microbiota isolated from healthy women exhibit probiotic properties and antimicrobial activity against pathogens isolated from cervical cancer patients., Ashwini Kamble, Shilpa Naik, Manju Talathi, Deepali Jadhav, Samradni Pingale, Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., Archieves of Microbiology,2022.
  • Folate mediated targeted delivery of cinnamaldehyde loaded and FITC functionalized magnetic nanoparticles in breast cancer: in vitro, in vivo and pharmacokinetic studies, Varsha Shetty, Alok Jakhade, Kavita Shinde, Rajeev Chikate and Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., New J. Chem., 2021.
  • Panchvalkala, a traditional Ayurvedic formulation, exhibits antineoplastic and immunomodulatory activity in cervical cancer cells and C57BL/6 mouse papilloma model., Shama Aphale, Kavita Shinde, Savita Pandita, Minal Mahajan, Prerna Raina, J N Mishra and Ruchika Kaul-Ghanekar., Cancer research Lab IRSHA BVDU., J Ethnopharmacol. Nov 2021.
  • Matairesinol, an active constituent of HC9 polyherbal formulation, exhibits HDAC8 inhibitory and anticancer activity. Minal Mahajan, Snehal Suryavanshi, Shovonlal Bhowmick, Fatmah Ali Alasmary, Tahani Mazyad Almutairi, Md Ataul Islam and Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., Biophysical Chemistry, Jun 2021.
  • Development and validation of bioanalytical HPLC method for simultaneous estimation of cinnamaldehyde and cinnamic acid in rat plasma: Application for pharmacokinetic studies., Varsha Shetty, Bothiraja, Chellampillai, Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., New Journal of Chemistry, 2020.
  • A polyherbal formulation, HC9 regulated cell growth and expression of cell cycle and chromatin modulatory proteins in breast cancer cell lines., Snehal Suryavanshi, Amit Choudhari, Prerna Raina, Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., J Ethnopharmacology., 2019.
  • Flax seed oil reduced tumor growth, modulated immune responses and decreased HPV E6 and E7 oncoprotein expression in a murine model of ectopic cervical cancer., Rashmi Deshpande, Prerna Raina, Kavita Shinde, Prakash Mansara, Manjiri Karandikar and Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., Prostaglandins and Other Lipid Mediators., 2019.
  • Effect of aqueous/methanolic extract of Ocimum sanctum (OciBest) on the Male and Female reproductive performance of wistar rats., P Raina, B Bharathi, A Senthilkumar, S Sagar, CV Chandrasekaran, D Prabhu, M Deepak, A Amit, R Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., Pharmacognosy Magazine, 2018.
  • Synthesis, characterization and antibacterial activity of ciprofloxacin loaded electrospun gelatin nanofibers. Ashwini Kamble, Varsha Shetty, S. M. Shendokar, S. S. Chavan and Ruchika Kaul-Ghanekar., Cancer Research Lab IRSHA BVDU., J Bionanosci. 2018.
  • Nardostachys jatamansi root extract modulates the growth of IMR-32 and SK-N-MC neuroblastoma cell lines through MYCN mediated regulation of MDM2 and p53. Suryavanshi S, Raina P, Deshpande R, Kaul-Ghanekar R., Cancer Research Lab IRSHA BVDU., Pharmacognosy Magazine., 2017.
  • Cinnamaldehyde, cinnamic acid and cinnamyl alcohol, the bioactives of Cinnamon cassia exhibit HDAC8 inhibitory activity-an in vitro and in silico study, Patil M, Choudhari A, Pandita S, Islam MA, Raina P, Kaul-Ghanekar R., Cancer Research Lab IRSHA BVDU., Pharmacognosy Magazine., 2017.
  • Degradation of doxorubicin to non-toxic metabolites using Fe-Ni bimetallic nanoparticles., Kadu, B.S., Wani, K.D., Kaul-Ghanekar, R. and Chikate, R.C., Cancer Research Lab IRSHA BVDU.,.Chemical Engineering Journal., 2017.
Patent Applications

A herbal composition (FC) for the treatment of cancer. Inventors: Dr. Ruchika Kaul Ghanekar, Dr. Amit Choudhary, Ms. Soumya Koppikar. Patent Application No: 2039/mum/2010