Mother & Child Health Department

Research Projects

Ongoing Projects

S.No Title Funding Agency Investigator
1 Understanding the association and underlying molecular mechanisms of early life ‘Double-burden’ of malnutrition and non-communicable disease risk in adolescence Department of Biotechnology, India Dr. Sadhana Joshi
2 Building evidence and designing solutions to prevent stillbirths in India- A collaborative approach to retrospectively analyze pregnancy cohorts in India Indian Council of Medical Research, Government of India Dr. Sadhana Joshi
3 Exploring the role of maternal fatty acids, placental fatty acid metabolism, and inflammation in determining infant health in gestational diabetes mellitus Department of Biotechnology, India Dr. Sadhana Joshi
4 OPTIMISE: Optimal preconception nutrition to offset inflammation and non-communicable disease risk in pregnant women and their children Medical Research Council, UK Dr. Sadhana Joshi
5 Early Interventions to Support Trajectories for Healthy Life in India (EINSTEIN). Healthy Life Trajectories Initiative (HeLTI) Department of Biotechnology, India Dr. Sadhana Joshi

Completed Projects

S.No Title Funding Agency Investigator
1 Centre for Advanced Research - Investigating Mechanisms Leading to Preeclampsia Indian Council of Medical Research, Government of India.
 
Dr. Sadhana Joshi
2 Epigenetic regulation of angiogenic factors in assisted reproductive technology (ART) and non-ART derived placentae Department of Biotechnology. Dr. Deepali Sundrani
3 Epigenetic regulation of placental peroxisome proliferator activated receptor (PPAR) in women delivering low birth weight babies Department of Biotechnology, Government of India.
 
Dr. Deepali Sundrani
4 Influence of Maternal One-carbon (1C) Metabolism in Placental Function, Fetal Growth and Programming Influence of Maternal One-carbon (1C) Metabolism in Placental Function, Fetal Growth and Programming Dr. Sadhana Joshi
5 Exploring the Role of Postnatal Omega-3 Fatty Acid Supplementation on Neuropeptide Y Levels in Offspring subjected to Maternal Separation using a Rat Model BVDU Dr. Anvita Kale
6 Pro-neurotrophins /p75NTR signalling contributes to increased apoptosis in preterm placentae Department of Biotechnology, India Dr. Preeti Gautam chavan
7 Disturbed maternal one carbon cycle in preeclampsia increases risk for cardio-metabolic variables in children Department of Biotechnology, India Dr. Sadhana Joshi
8 Regional differences in neurotrophin regulation of vascularization in preeclamptic placentae Indian Council of Medical Research, India Dr. Sadhana Joshi
9 Exploring the efficacy of omega 3 fatty acid supplementation to a maternal high fat diet deficient in vitamin b12 in ameliorating the risk for impaired brain development and metabolic syndrome in the offspring. Indian Council of Medical Research, India Dr. Sadhana Joshi
10 Regulation of fatty acid desaturases and transport protein in pregnancy Indian Council of Medical Research, India Dr. Sadhana Joshi
11 Maternal micronutrient status, inflammatory markers and Risk for non-communicable diseases in the offspring in a preeclamptic rat model Department Biotechnology, India Dr. Sadhana Joshi
12 Understanding the Risk of Metabolic and Neurodevelopmental Disorders in Infants Born to Mothers with Pregnancy Complications Wellcome trust, UK Dr. Sadhana Joshi
13 Multigenerational effects of vitamin B12 deficiency /supplementation on brain development and metabolic syndrome variables in a rat model. Department of Science and Technology, India Dr. Sadhana Joshi
14 Epigenetic regulation of matrix metalloproteinases in preterm placenta Department of Science and Technology, India Dr. Deepali Sundrani
15 Gene Specific Methylation Patterns of Angiogenic Factors in Preeclampsia Indian Council of Medical Research, India Dr. Sadhana Joshi
16 Effect of micronutrient rich dietary supplementation on the fatty acid profile, antioxidant enzymes and markers of oxidative stress in women living in urban slums Wellcome Trust, UK Dr. Sadhana Joshi
17 Role of long chain polyunsaturated fatty acids, neurotrophins and vascular endothelial growth factor in mothers with pre-eclampsia and their association with infant growth Indian Council of Medical Research, India Dr. Sadhana Joshi
18 Comparison of plasma & placental proteomic patterns in pregnancy complications Department Biotechnology, India Dr. Sadhana Joshi
19 Role of maternal micronutrients on brain neurotrophic factors and cognitive development in Wistar rat offspring Department Biotechnology, India Dr. Sadhana Joshi
20 Medhya activity of jatamansi (nardostachys jatamansi) with respect to its Adulterants and substitutes as evaluated by ADHD (attention deficit hyperactivity disorder) model National Medicinal Plants Board (NMPB), Department of AYUSH, India Dr. Sadhana Joshi
21 Investigations on long term effects of maternal folic acid supplementation for reducing risks associated with non-communicable diseases in adult offspring using rat model Department Biotechnology, India Dr. Sadhana Joshi